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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Synthetic peptide (Human).|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-20878 detects Cardiac Troponin 1 in Human samples.
MA1-20878 has been successfully used in ELISA procedures.
MA1-20878 immunogen corresponds to Synthetic peptide (Human)..
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATP-ase activity of acto-myosin and TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cardiomyopathy, dilated 2A (autosomal recessive); CMD2A; CMH7; cTnI; MGC116817; RCM1; TNNC1; troponin I type 3 (cardiac)
CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1; TNNI3