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|Tested species reactivity||Dog, Human, Mouse, Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Free, human cardiac troponin and/or native troponin complex.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-20121 detects cardiac troponin 1 in human, mouse, rat and canine samples.
MA1-20121 has been successfully used in ELISA and Western blot procedures.
The MA1-20121 immunogen is free, human cardiac troponin and/or native troponin complex.
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. E.g. TnI inhibits ATP-ase activity of acto-myosin. TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI). cTnI is expressed only in myocardium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cardiac troponin I; cardiomyopathy, dilated 2A (autosomal recessive); CMD2A; CMH7; cTnI; MGC116817; RCM1; TNNC1; troponin 1, type 3; troponin I type 3 (cardiac); troponin I, cardiac muscle
CMD1FF; CMD2A; CMH7; Ctni; RCM1; Tn1; TnI; TNNC1; TNNI3