The synthetic peptide sequence is 223-242aa, KARKTNPEIQSTLRKRLYLQ
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apoptosis-related cysteine protease; CASP-14; CASP14; caspase 14, apoptosis-related cysteine peptidase; caspase 14, apoptosis-related cysteine protease; Caspase-14; Caspase-14 subunit p10; Caspase-14 subunit p10, mature form; Caspase-14 subunit p17; Caspase-14 subunit p17, mature form; Caspase-14 subunit p20; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8; Caspase-14 subunit p8, intermediate form; intermediate form; mature form; MICE; Mini-ICE
Gene Aliases: CASP14; MICE; mini-ICE