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|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide, conjugated to KLH, corresponding to residues K(119) E R A E E I Y P I K E R N N(133) of human Caspase 4.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||1 - 2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24698 detects Caspase 4 from human and monkey samples.
MA1-24698 has been successfully used in Western blot procedures.
The MA1-24698 immunogen is a synthetic peptide, conjugated to KLH, corresponding to residues K(119) E R A E E I Y P I K E R N N(133) of human Caspase 4.
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
apoptotic cysteine protease Mih1/TX; CASP-4; caspase 4, apoptosis-related cysteine protease; caspase-4; ICE(rel)-II; ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; protease ICH-2; protease TX; TX
ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; TX