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|Tested species reactivity||Human|
|Published species reactivity||Sheep, Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human Caspase 9 pro-domain protein.|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:250|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
Suggested positive control: HEK 293 whole cell lysate.
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The expressions of HSP70 and αB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs.
MA1-16842 was used in immunohistochemistry to study the expression of HSP70 and alphaB-crystallin in myocarditis associated with foot-and-mouth disease virus in lambs
|Gulbahar MY,Kabak YB,Karayigit MO,Yarim M,Guvenc T,Parlak U||Journal of veterinary science (12:65)||2011|
Ovarian expression of markers associated with proliferation or apoptosis in women with diminished ovarian reserve.
MA1-16842 was used in immunohistochemistry to investigate the expression of molecular markers involved in cell cycle regulation in ovaries of women with diminished ovarian reserve
|Vital-Reyes V,Rodríguez-Burford C,Chhieng DC,Alvarado-Cabrero I,Reyes-Fuentes A,Grizzle WE||Fertility and sterility (86:176)||2006|
APAF-3; APAF3; apoptotic protease activating factor 3; apoptotic protease MCH-6; cas9; caspase 9, apoptosis-related cysteine peptidase; CASPASE-9c; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; protein phosphatase 1, regulatory subunit 56; RP11-265F14.3
APAF-3; APAF3; CASP9; ICE-LAP6; MCH6; PPP1R56