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Proteintech
Caspase 9/p35/p10 Polyclonal Antibody, CoraLite® Plus 488
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FIGURE: 1 / 1
Caspase 9/p35/p10 Antibody (CL48810380100UL) in Flow
1X10^6 HepG2 cells were intracellularly stained with 0.4 µg CoraLite 488 Anti-Human Caspase 9/p35/p10 (Product # CL48810380100UL)) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
CL48810380100UL
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Conjugate
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 25 kDa caspase-9 dominant negative protein; apoptotic protease activating factor 3; apoptotic protease MCH-6; apoptotic protease-activating factor 3; carboxy-terminal divergent isoform; CASP9; caspase 9, apoptosis-related cysteine peptidase; caspase 9b; caspase-9 dominant negative form; caspase-9 variant; caspase-9-carboxyl-terminal divergent; ICE-like apoptotic protease 6; protein phosphatase 1, regulatory subunit 56; unnamed protein product
Gene Aliases: APAF-3; APAF3; CASP-9; Casp-9-CTD; Casp9_v1; Caspase-9; ICE-LAP6; MCH6; PPP1R56
UniProt ID: (Human) P55211, (Mouse) Q8C3Q9
Entrez Gene ID: (Human) 842, (Mouse) 12371, (Rat) 58918
response to hypoxia
kidney development
response to ischemia
proteolysis
apoptotic process
cellular response to DNA damage stimulus
intrinsic apoptotic signaling pathway in response to DNA damage
response to UV
protein processing
response to cobalt ion
response to estradiol
response to lipopolysaccharide
glial cell apoptotic process
cellular response to UV
signal transduction in response to DNA damage
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
response to ethanol
protein maturation
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to dexamethasone stimulus
response to indole-3-methanol
leukocyte apoptotic process
response to anesthetic
intrinsic apoptotic signaling pathway
positive regulation of execution phase of apoptosis
response to auditory stimulus
animal organ development
system development
platelet formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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