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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Cathepsin D isolated from human liver.|
|Storage buffer||PBS with 1% BSA|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:75|
|Immunohistochemistry (Paraffin) (IHC (P))||1:75|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-26253 detects Cathepsin D from human samples.
PA1-26253 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-26253 immunogen is Cathepsin D isolated from human liver.
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cathepsin D; ceroid-lipofuscinosis, neuronal 10; CLN10; CPSD; epididymis secretory sperm binding protein Li 130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease; MGC2311
CLN10; CPSD; CTSD; HEL-S-130P