This antibody detects human pro and active Cathepsin E in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 40% cross-reactivity with recombinant mouse Cathepsin E is observed and less than 2% cross-reactivity with recombinant human (rh) Cathepsin D and rhBACE is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cathepsin E; Cathepsin E form I; Cathepsin E form II; EC 188.8.131.52; erythrocyte membrane aspartic proteinase; slow-moving proteinase
Gene Aliases: CATE; CTSE
UniProt ID: (Human) P14091
Entrez Gene ID: (Human) 1510