|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant protein corresponding to 124aa from N terminus of human cathepsin G|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:40|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12473 targets Cathepsin G in IHC (P) applications and shows reactivity with Human samples.
The MA5-12473 immunogen is recombinant protein corresponding to 124aa from N terminus of human cathepsin G.
Cathepsin G is a serine protease found in azurophilic granules of neutrophils involved in phagocytic lysis of engulfed forein particles. It is also involved in NK cell cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cathepsin G-dependent modulation of platelet thrombus formation in vivo by blood neutrophils.
MA5-12473 was used in western blot to study the role of neutrophil cathepsin G in the regulation of platelet thrombus formation
|Faraday N,Schunke K,Saleem S,Fu J,Wang B,Zhang J,Morrell C,Dore S||PloS one (8:null)||2013|
In vitro resistance mechanisms of Neisseria meningitidis against neutrophil extracellular traps.
MA5-12473 was used in immunocytochemistry to study the mechanisms underlying the resistance of Nesseria meningitidis to neutrophil extracellular traps
|Lappann M,Danhof S,Guenther F,Olivares-Florez S,Mordhorst IL,Vogel U||Molecular microbiology (89:433)||2013|