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Cdc40 Antibody (MA5-38004) in IHC (P)
Immunohistochemistry analysis of Cdc40 in paraffin-embedded mouse liver. Samples were incubated with Cdc40 Monoclonal antibody (Product # MA5-38004) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-38004
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC2321
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.28 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897922
Product Specific Information
Positive Samples: HeLa, HCT116, HepG2, Mouse lung, Mouse brain, Mouse spleen, Rat lung
Immunogen sequence: MSAAIAALAA SYGSGSGSES DSDSESSRCP LPAADSLMHL TKSPSSKPSL AVAVDSAPEV AVKEDLETGV HLDPAVKEVQ YNPTYETMFA PEFGPENPFR
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; hPRP17; pre-mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17 homolog
Gene Aliases: 1200003H23Rik; CDC40; EHB3; PRP17; PRPF17
UniProt ID: (Human) O60508, (Mouse) Q9DC48
Entrez Gene ID: (Human) 51362, (Mouse) 71713, (Rat) 361859
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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