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Proteintech
Ceruloplasmin Monoclonal Antibody (3C8A5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
66156-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3C8A5
Immunogen
Ceruloplasmin Fusion Protein Ag15535 (194-446 aa encoded by BC146663)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.89 mg/mL
Amount
133.5 µg
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IGPLIICKK DSLDKEKEKH IDREFVVMFS VVDENFSWYL EDNIKTYCSE PEKVDKDNED FQESNRMYSV NGYTFGSLPG LSMCAEDRVK WYLFGMGNEV DVHAAFFHGQ ALTNKNYRID TINLFPATLF DAYMVAQNPG EWMLSCQNLN HLKAGLQAFF QVQECNKSSS KDNIRGKHVR HYYIAAEEII WNYAPSGIDI FTKENLTAPG SDSAVFFEQG TTRIGGSYKK LVYREYTDAS FTNRKERGPE EEHL (194-446 aa encoded by B C146663)
Target Information
Ceruloplasmin encodes a protein that is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bilitranslocase; caeruloplasmin; cell surface ferroxidase; ceruloplasmin; ceruloplasmin (ferroxidase); cuproxidase ceruloplasmin; ferroxidase ceruloplasmin; glutathione peroxidase ceruloplasmin; glutathione-dependent peroxiredoxin ceruloplasmin; preceruloplasmin (EC 1.16.3.1); unnamed protein product
Gene Aliases: AB073614; CERP; CP-2
UniProt ID: (Human) P00450
Entrez Gene ID: (Human) 1356, (Rat) 24268
ferroxidase activity
glutathione peroxidase activity
copper ion binding
oxidoreductase activity
oxidoreductase activity, oxidizing metal ions
oxidoreductase activity, oxidizing metal ions, oxygen as acceptor
peroxidase inhibitor activity
phospholipid-hydroperoxide glutathione peroxidase activity
chaperone binding
cellular copper ion homeostasis
cellular iron ion homeostasis
cellular oxidant detoxification
liver development
inflammatory response
mitochondrion organization
female pregnancy
response to nutrient
lactation
gene expression
plasma membrane copper ion transport
lipid catabolic process
fatty acid oxidation
lung development
response to insulin
glucose homeostasis
response to copper ion
mammary gland involution
CAMKK-AMPK signaling cascade
protein-containing complex assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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