|Tested species reactivity||Human|
|Published species reactivity||Human, Rhesus monkey|
|Host / Isotype||Mouse / IgG1, kappa/IgG2a, kappa|
|Clone||CG04 + CG05|
|Immunogen||Purified beta-subunit of HCG|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-11324 targets Chorionic Gonadotropin Human in IHC (P) applications and shows reactivity with Human samples.
The MA5-11324 immunogen is purified beta-subunit of HCG.
Human Chorionic Gonadotropin (HCG) is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha- and beta-subunits. The alpha-subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP), and HCG but negative for EMA and AFP is probably a choriocarcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Rhesus monkey||Not Cited||
Non-gestational malignant placental site trophoblastic tumor of the ovary in a 4-year-old rhesus monkey.
MA5-11324 was used in immunohistochemistry to report on a case of non-gestational malignant placental site trophoblastic tumor of the ovary in a 4-year-old rhesus monkey
|Marbaix E,Defrère S,Duc KH,Lousse JC,Dehoux JP||Veterinary pathology (45:375)||2008|
Dedifferentiated Liposarcoma of the Retroperitoneum with Extensive Leiomyosarcomatous Differentiation and beta-Human Chorionic Gonadotropin Production.
MA5-11324 was used in immunohistochemistry to report a clinical case of dedifferentiated liposarcoma of the retroperitoneum with unique features
|Russell MJ,Flynt FL,Harroff AL,Fadare O||Sarcoma (2008:null)||2008|
The immunoexpressions and prognostic significance of inhibin alpha and beta human chorionic gonadotrophins (HCG) in breast carcinomas.
MA5-11324 was used in immunohistochemistry and western blot to study the expression and prognostic value of inhibin alpha and beta human chorionic gonadotrophins in breast carcinomas
|Chang E,Lee E,Oh SJ,Kim JS,Kang C||Cancer research and treatment : official journal of Korean Cancer Association (37:241)||2005|
Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes.
MA5-11324 was used in immunohistochemistry and western blot to study the differential expression of LIGHT in human placental villi and amniochorion membranes
|Gill RM,Ni J,Hunt JS||The American journal of pathology (161:2011)||2002|
FLICE-inhibitory protein: expression in early and late gestation human placentas.
MA5-11324 was used in immunocytochemistry to investigate the role of FLICE-inhibitory protein in early and late gestation human placentas
|Ka H,Hunt JS||Placenta (27:626)||2006|
Isolation and culture of term human trophoblast cells.
MA5-11324 was used in immunocytochemistry to develop methods for the isolation and long-term culture of human trophoblast cells from term placentas
|Petroff MG,Phillips TA,Ka H,Pace JL,Hunt JS||Methods in molecular medicine (121:203)||2005|
Temporal and spatial patterns of expression of inhibitors of apoptosis in human placentas.
MA5-11324 was used in immunocytochemistry to investigate the effect of inhibitors of apoptosis on placental cell survival
|Ka H,Hunt JS||The American journal of pathology (163:413)||2003|