|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||1/10 - 1/40|
|Immunohistochemistry (IHC)||See 13 publications below|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Non-human primate, Pig|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human pheochromocytoma tissue.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
A suggested positive control for immunohistochemical applications is normal pancreas. This product does not require protein digestion pre-treatment of paraffin sections.
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: betagranin (N-terminal fragment of chromogranin A); cgA; chromogranin-A; pancreastatin; parathyroid secretory protein 1; pituitary secretory protein I; SP-I
Gene Aliases: CGA
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