Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Immunohistochemistry (IHC) |
- | View 11 publications 11 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
0.5-1.0 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Non-human primate |
Published species |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
PHE5 |
Immunogen |
Human pheochromocytoma |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.4, with 0.2% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
RRID |
AB_10977528 |
MA5-13281 targets Chromogranin A in IF and IHC (P) applications and shows reactivity with Human and Non-human primate samples.
The MA5-13281 immunogen is human pheochromocytoma.
Chromogranin A (CHGA) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides act as autocine or paracrine negative modulators of the neuroendocrine system. CHGA is an excellent marker for carcinoid tumors, pheo-chromocytomas, paragangliomas, and other neuro-endocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AL-11; betagranin (N-terminal fragment of chromogranin A); Catestatin; CgA; chromofungin; Chromogranin-A; CTNNB; DKFZp686D02253; EA-92; ER-37; ES-43; FLJ25606; FLJ37923; GE-25; GR-44; GV-19; LF-19; MGC105435; p-Glu serpinin precursor; Pancreastatin; parathyroid secretory protein 1; Pituitary secretory protein I; Serpinin; Serpinin-RRG; SL21; SP-I; SS-18; Vasostatin I; Vasostatin II; Vasostatin-1; Vasostatin-2; WA-8; WE-14
Gene Aliases: CGA; CHGA
UniProt ID: (Human) P10645
Entrez Gene ID: (Human) 1113
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