PA1-10838 detects Secretogranin II from human and rat samples.
PA1-10838 has been successfully used in Western blot, immunohistochemistry, and immunoprecipitation applications.
The PA1-10838 immunogen is N-terminal sequence (aa 1-19) of rat/human secretogranin II coupled to ovalbumin.
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chromogranin C (Secretogranin II); Chromogranin-C; Manserin; secretogranin 2; Secretogranin II; secretogranin II (chromogranin C); Secretogranin-2; Secretoneurin; SgII; SN
Gene Aliases: Chcg; CHGC; EM66; Scg-2; SCG2; SgII; SN