The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
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Protein Aliases: Chromogranin C (Secretogranin II); Chromogranin-C; Manserin; secretogranin 2; Secretogranin II; secretogranin II (chromogranin C); Secretogranin-2; Secretoneurin; SgII; SN
Gene Aliases: Chcg; CHGC; EM66; Scg-2; SCG2; SgII; SN