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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Mixture of two peptides from the middle and C-terminal regions of human claudin-10 protein|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:50|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Claudin proteins are a family of proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact; made up of network of strands to act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
||Minimal effects of VEGF and anti-VEGF drugs on the permeability or selectivity of RPE tight junctions.||Peng S,Adelman RA,Rizzolo LJ||Investigative ophthalmology & visual science (51:3216)||2010|
|Human||1:300||Minimal effects of VEGF and anti-VEGF drugs on the permeability or selectivity of RPE tight junctions.||Peng S,Adelman RA,Rizzolo LJ||Investigative ophthalmology & visual science (51:3216)||2010|
Molecular staging of epithelial maturation using secretory cell-specific genes as markers.
41-5100 was used in immunohistochemistry - frozen section to identify Clara cell-specific genes using chemical and transgenic approaches to ablate Clara cells.
|Zemke AC,Snyder JC,Brockway BL,Drake JA,Reynolds SD,Kaminski N,Stripp BR||American journal of respiratory cell and molecular biology (40:340)||2009|
claudin 10A; claudin 10B; claudin-10; claudin-10A; CPETRL3; OSP-L; OSP-like protein
6720456I16Rik; CLDN10; Cldn10a; Cldn10b; CPETRL3; D14Ertd728e; OSP-L