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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 15 and 218 of Human Claudin 5|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30193 targets Claudin 5 in WB applications and shows reactivity with Human samples.
The PA5-30193 immunogen is recombinant fragment corresponding to a region within amino acids 15 and 218 of Human Claudin 5.
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AWAL; Claudin-5; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome
AWAL; BEC1; CLDN5; CPETRL1; TMVCF