Immunogen sequence: RVFGNKKQLK ILTDIMWPII AKLAREEMDR AVAEGKRVCV IDAAVLLEAG WQNLVHEVWT AVIPETEAVR RIVERDGLSE AAAQSRLQSQ MSGQQLVEQS HVVLSTLWEP HITQRQVEKA WALLQKRIPK THQ
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 184.108.40.206) and dephospho-CoA kinase (DPCK; EC 220.127.116.11), in prokaryotes (Daugherty et al., 2002 [PubMed 11923312]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bifunctional coenzyme A synthase; bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase; CoA synthase; Coenzyme A synthase; Dephospho-CoA kinase; Dephospho-CoA pyrophosphorylase; Dephosphocoenzyme A kinase; DPCK; DPCOAK; NBP; nucleotide binding protein; Pantetheine-phosphate adenylyltransferase; Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase; POV-2; PPAT; UKR1
Gene Aliases: 1300003G02Rik; COASY; DPCK; NBIA6; NBP; pOV-2; PPAT; PSEC0106; UKR1