|Immunoprecipitation (IP)||2 ug|
|Western Blot (WB)||0.5 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Recombinant human protein purified from E.coli (His-Coilin)|
|Storage buffer||HEPES with 0.15M NaCl, 0.01% BSA, 50% glycerol|
|Contains||0.03% sodium azide|
A suggested positive control for this product is HeLa cell lysate.
Coilin is a component of the nuclear Cajar (coiled) bodies (CBs) which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs. Human coilin is a 576-amino acid protein found enriched in CBs, but is also found in large amounts in the nucleoplasm. Coilin is a constitutive phosphoprotein that is hyperphosphorylated during mitosis and it is thought that hyperphosphorylation triggers CB disassembly during cell replication. Self-interaction and localization have been shown to depend on the phosphorylation state of coilin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CLN80; Coilin; coilin p80; p80; p80-coilin
Gene Aliases: CLN80; COIL; p80-coilin
UniProt ID: (Human) P38432
Entrez Gene ID: (Human) 8161
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