Invitrogen

Coilin Recombinant Rabbit Monoclonal Antibody (ARC0785)

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Coilin Antibody in Western Blot (WB) — Western Blot analysis of Coilin performed on various cell lines using a Coilin monoclonal antibody (Product # MA5-35373) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000.

Product Details

MA5-35373

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-

Product Specifications
Species Reactivity	Human, Rat
Host/Isotype	Rabbit / IgG
Class	Recombinant Monoclonal
Type	Antibody
Clone	ARC0785
Immunogen	A synthesized peptide derived from human Coilin
Conjugate	Unconjugated
Form	Liquid
Concentration	0.633 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2849274

Target Information

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.