This antibody shows <0.5% cross-reactivity with porcine albumin and immunoglobulins.
Reconstitute with 0.5 mL of distilled water or saline. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles.
Rabbit anti Porcine collagen I/III antibody reacts with native and heat denatured porcine collagen type 1 and 3.Less than 0.5% reactivity is observed with porcine albumin and immunoglobulins.
Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha1 chain of type I collagen; alpha2 chain of type I collagen; COL1A1; COL1A1; matrix protein; Collagen 1; Collagen 3; collagen type I alpha 1; collagen, type I, alpha 2; collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant); type III collagen