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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Purified native collagen type I, II, III, IV and V.|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||whole serum with mannitol, dextran|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||1:200|
|Western Blot (WB)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 1 ml of distilled water and add preservative if preferred.
Type I collagen, the fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AB collagen; alpha 2 type I procollagen; alpha 2(I) procollagen; alpha 2(I)-collagen; alpha-1 type I collagen; alpha-1 type II collagen; alpha-2 type I collagen; alpha1 (III) collagen; alpha1(I) procollagen; arresten; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; chondrocalcin; COL4A1 NC1 domain; collagen alpha 1 chain type I; collagen alpha-1(I) chain preproprotein; collagen I, alpha-2 polypeptide; collagen II, alpha-1 polypeptide; collagen IV, alpha-1 polypeptide; Collagen IV, alpha-4 polypeptide; collagen IV, alpha-5 polypeptide; collagen IV, alpha-6 polypeptide; collagen of basement membrane, alpha-1 chain; collagen of basement membrane, alpha-4 chain; collagen of basement membrane, alpha-5 chain; collagen of basement membrane, alpha-6; collagen of skin, tendon and bone, alpha-1 chain; collagen of skin, tendon and bone, alpha-2 chain; collagen, fetal; collagen, fetal membrane, A polypeptide; collagen, type I, alpha 1; collagen, type I, alpha 2; collagen, type II, alpha 1; collagen, type III, alpha 1; collagen, type IV, alpha 1; collagen, type IV, alpha 4; collagen, type IV, alpha 5; collagen, type IV, alpha 6; collagen, type V, alpha 1; collagen, type V, alpha 2; collagen, type V, alpha 3; dA149D17.3; dA24A23.1; dJ889N15.4 (Collagen Alpha 6(IV)); Ehlers-Danlos syndrome type IV, autosomal dominant; pro-(alpha)3(V) collagen; pro-alpha-1 collagen type 1; type I proalpha 1; type I procollagen; type I procollagen alpha 1 chain; type V preprocollagen alpha 2 chain
ANFH; AOM; ASLN; ATS; BSVD; CA44; CA54; COL11A3; COL1A1; COL1A2; COL2A1; COL3A1; COL4A1; COL4A2; COL4A4; COL4A5; COL4A6; COL5A1; COL5A2; COL5A3; CXDELq22.3; DELXq22.3; DFNX6; EDS4A; EDSC; ICH; OI1; OI2; OI3; OI4; POREN2; RATOR; SEDC; STL1