Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
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Protein Aliases: alpha 1 type IV collagen; alpha1(IV) collagen; Arresten; COL4A1 NC1 domain; Collagen 4; Collagen alpha-1(IV) chain; Collagen IV; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; collagen, type IV, alpha 1; Collagen-4; Collagen-IV; Collagen4; CollagenIV; Del(8)Bru44H; procollagen, type IV, alpha 1; retinal anterior wiring
Gene Aliases: Bru; BSVD; Col4a-1; COL4A1; Del(8)44H; RATOR; Raw; Svc