MA5-13437 targets Collagen IV in IHC (P) applications and shows reactivity with Bovine and Human samples.
The MA5-13437 immunogen is human glomeruli.
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha-1 chain; alpha-1 polypeptide; Arresten; Canstatin; COL4A1 NC1 domain; Collagen alpha-1(IV) chain; Collagen alpha-2(IV) chain; Collagen alpha-3(IV) chain; Collagen alpha-4(IV) chain; collagen IV; collagen IV, alpha-1 polypeptide; collagen IV, alpha-3 polypeptide; Collagen IV, alpha-4 polypeptide; collagen of basement membrane; collagen of basement membrane, alpha-1 chain; collagen of basement membrane, alpha-4 chain; collagen, type IV, alpha 1; collagen, type IV, alpha 3 (Goodpasture antigen); collagen, type IV, alpha 4; Goodpasture antigen; Tumstatin
Gene Aliases: BOS_12713; BOS_2161; BOS_2253; BSVD; CA44; COL4A1; COL4A2; COL4A3; COL4A4; ICH; POREN2; RATOR