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|Tested species reactivity||Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (TVQYSDDPRTEF) corresponding to the internal amino acids of COL7A1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-1.5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with canine, human, mouse and porcine based on sequence homology.
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
alpha 1 type VII collagen; alpha-1 polypeptide; COL7A1; collagen alpha-1(VII) chain; collagen VII; Collagen, type VII; collagen, type VII, alpha 1; collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive); EBD1; EBDCT; EBR1; HGNC:2214; long chain collagen; procollagen, type VII, alpha 1