Invitrogen

Complement C3d Monoclonal Antibody (053A-1149.3.1.4 (1003))

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1/5000

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

Assay Dependent

Flow Cytometry (Flow)

Assay Dependent

ELISA (ELISA)

Assay Dependent

Product Specifications

Species Reactivity

Human

Published species

Baboon

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

053A-1149.3.1.4 (1003)

Immunogen

Purified C3d from human plasma.

Conjugate

Unconjugated

Form

Liquid

Concentration

1.14 mg/mL

Purification

Protein A

Storage buffer

BBS, pH 8.4

Contains

0.1% sodium azide

Storage conditions

4°C or -20°C if preferred

RRID

AB_930156

Product Specific Information

Mouse anti Human C3d antibody, clone 053A-1149.3.1.4 recognizes human complement component 3d (C3d), a approximately 33 kDa polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d.

Target Information

C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Acylation stimulating protein; acylation-stimulating protein cleavage product; ASP; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3-beta-c; C3a anaphylatoxin; C3adesArg; C3bc; Cd3; Complement C3; Complement C3 alpha chain; Complement C3 beta chain; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; prepro-C3

Gene Aliases: AHUS5; ARMD9; ASP; C3; C3a; C3b; CPAMD1; HEL-S-62p

UniProt ID: (Human) P01024

Entrez Gene ID: (Human) 718

Molecular Function: complement component cytokine defense/immunity protein enzyme modulator protease inhibitor serine protease inhibitor signaling molecule