GAU 008-01B-01 detects Complement factor D in human samples.
GAU 008-01B-01 has been successfully used in ELISA procedures.
GAU 008-01B-01 immunogen is human factor D.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Complement factor D is a serine protease of the alternative pathway of complement activation. The protein is a single chain polypeptide with a molecular mass of 25 kDa. Factor D cleaves factor B bound to C3b, generating the alternative pathway C3 convertase C3bBb and releasing the Ba fragment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adipsin; C3 convertase activator; Complement factor D; complement factor D (adipsin); complement factor D preproprotein; D component of complement (adipsin); EC 126.96.36.199; Properdin factor D
Gene Aliases: ADIPSIN; ADN; CFD; DF; PFD
UniProt ID: (Human) P00746
Entrez Gene ID: (Human) 1675