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Product Details
PA5-11644
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
KLH conjugated synthetic peptide between 402-433 amino acids from the C-terminal region of human Connexin 50 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1.6 mg/mL |
Purification |
Ammonium sulfate precipitation, Size-exclusion - Dialysis |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2247584 |
Product Specific Information
This antibody is predicted to react with chicken based on sequence homology.
Target Information
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 8 connexin; cell surface glycoprotein; connexin 50; Connexin-50; Cx50; gap junction alpha 8; Gap junction alpha-8 protein; gap junction membrane channel protein alpha 8; gap junction membrane channel protein alpha-8; gap junction protein alpha 8 50kDa; Lens fiber protein MP70; lens intrinsic membrane protein MP70; lens opacity 10
Gene Aliases: Aey5; CAE; CAE1; Cnx50; CTRCT1; CX50; CZP1; GJA8; Lop10; MP70
UniProt ID: (Human) P48165, (Mouse) P28236
Entrez Gene ID: (Human) 2703, (Mouse) 14616
Molecular Function:
gap junction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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