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Product Details
PA5-82510
| Applications | Tested Dilution | Publications |
|---|---|---|
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human GJA8 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.05 mg/mL |
Purification |
Anitgen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2789668 |
Product Specific Information
Immunogen sequence: SLHSIAVSSI QKAKGYQLLE EEKIVSHYFP LTEVGMVETS PLPAKPFNQF EEKISTGPLG DLSRGYQETL PSYAQVGAQE VEGEGPPAEE GAEPEVGEKK EEAERLTTEE QEKVAVPEGE KVETPGVDKE GEKEEPQSEK VSKQGLP
Target Information
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell surface glycoprotein; connexin 50; Connexin-50; Cx50; gap junction alpha 8; Gap junction alpha-8 protein; gap junction membrane channel protein alpha-8; gap junction protein alpha 8 50kDa; Lens fiber protein MP70; lens intrinsic membrane protein MP70
Gene Aliases: CAE; CAE1; CTRCT1; CX50; CZP1; GJA8; MP70
UniProt ID: (Human) P48165
Entrez Gene ID: (Human) 2703
Molecular Function:
gap junction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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