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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 547 and 762 of Human Ctip1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30636 targets Ctip1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30636 immunogen is recombinant protein fragment corresponding to a region within amino acids 547 and 762 of Human Ctip1.
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A-L; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF-interacting protein 1; CTIP1; ecotropic viral integration site; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein homolog; EVI-9; EVI9; HBFQTL5; zinc finger protein 856; ZNF856
BCL11A; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; CTIP1; EVI9; HBFQTL5; KIAA1809; ZNF856