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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.1-1 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
2-10 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
E23.1 |
Immunogen |
A synthetic peptide of human Cyclin A2 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with proprietary stabilizer |
Contains |
0.01% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Positive control: Breast carcinoma
Cellular location: Nuclear.
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cyclin A; Cyclin-A; Cyclin-A2
Gene Aliases: CCN1; CCNA; CCNA2
UniProt ID: (Human) P20248
Entrez Gene ID: (Human) 890
Molecular Function:
kinase activator
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