Invitrogen

Cyclin D2 Monoclonal Antibody (DCS-3.1)

Product Details

AHF0112

Applications	Tested Dilution	Publications
Western Blot (WB)	Assay-dependent	View 3 publications 3 publications
Immunocytochemistry (ICC/IF)	Assay-dependent	-
Flow Cytometry (Flow)	Assay-dependent	View 1 publication 1 publication
Immunoprecipitation (IP)	Assay-Dependent	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Rat
Host/Isotype	Mouse / IgG2a, kappa
Class	Monoclonal
Type	Antibody
Clone	DCS-3.1
Immunogen	Purified histidine-tagged human recombinant full length cyclin D2 protein. View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.2 mg/mL
Purification	Protein A
Storage buffer	PBS, pH 7.4, with 0.2% BSA
Contains	0.09% sodium azide
Storage conditions	4° C
RRID	AB_2536297

Target Information

Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

p75NTR enhances PC12 cell tumor growth by a non-receptor mechanism involving downregulation of cyclin D2.

Experimental cell research

Fritz MD,Mirnics ZK,Nylander KD,Schor NF

AHF0112 was used in western blot to elucidate how p75NTR suppresses cyclin D2 expression in PC12 cells

Sun Oct 15 00:00:00 EDT 2006

Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells.

Molecular endocrinology (Baltimore, Md.)

Cheng G,Lewis AE,Meinkoth JL

AHF0112 was used in western blot to study the effect of activated Ras in rat thyroid cells.

Sat Mar 01 00:00:00 EST 2003

Ras stimulates aberrant cell cycle progression and apoptosis in rat thyroid cells.

Molecular endocrinology (Baltimore, Md.)

Cheng G,Lewis AE,Meinkoth JL

AHF0112 was used in western blot to study the effect of activated Ras in rat thyroid cells.

Sat Mar 01 00:00:00 EST 2003

Differential regulation of p27(Kip1) expression by mitogenic and hypertrophic factors: Involvement of transcriptional and posttranscriptional mechanisms.

The Journal of cell biology

Servant MJ,Coulombe P,Turgeon B,Meloche S

AHF0112 was used in Western Blotting to examine the downstream effects of platelet-derived growth factor-BB and Angiotensin II on regulators of the cell cycle machinery in rat aortic smooth muscle cells.