Recommended positive controls: HepG2, NIH-3T3.
Predicted reactivity: Mouse (95%), Rat (94%), Pig (91%), Rhesus Monkey (97%), Bovine (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
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Protein Aliases: 40 kDa peptidyl-prolyl cis-trans isomerase; 40 kDa peptidyl-prolyl cis-trans isomerase D; cyclophilin 40; cyclophilin D; Cyclophilin-40; Cyclophilin-related protein; Cyp 40; Cyp D; CYP-40; cytoplasmic cyclophilin D; EC 184.108.40.206; MGC33096; Peptidyl-prolyl cis-trans isomerase D; peptidylprolyl isomerase D; PPIase D; rotamase; Rotamase D; testicular tissue protein Li 147
Gene Aliases: 4930564J03Rik; CYP-40; CYP40; CYPD; I79_011990; PPID; Ppidl; Ppif
Molecular Function: isomerase