This Antibody was verified by KnockOut to ensure that the antibody binds to the antigen stated. View Details
PA5-27326 targets Cytochrome P450 Reductase in IF and WB applications and shows reactivity with Human samples.
The PA5-27326 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 243 of Human Cytochrome P450 Reductase.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CPR; CYPOR; NADPH--cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R
Gene Aliases: CPR; CYPOR; P450R; POR
UniProt ID: (Human) P16435
Entrez Gene ID: (Human) 5447