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NeoBiotechnologies
Cytochrome p450 Monoclonal Antibody (M12P4H2)
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Product Details
1571-MSM1-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
M12P4H2
Immunogen
Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CYP2C9 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C9 localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: (R)-limonene 6-monooxygenase; (S)-limonene 6-monooxygenase; (S)-limonene 7-monooxygenase; (S)-mephenytoin hydroxylase associated cytochrome P450; 4-nitrophenol 2-hydroxylase; Cholesterol 25-hydroxylase; CYPIIC17; CYPIIC18; CYPIIC19; CYPIIC8; CYPIIC9; CYPIIE1; cytochrome P-450 1; cytochrome P-450 II C; cytochrome P-450 S-mephenytoin 4-hydroxylase; Cytochrome P-450MP; Cytochrome P450 2C18; Cytochrome P450 2C19; Cytochrome P450 2C8; Cytochrome P450 2C9; Cytochrome P450 2E1; Cytochrome P450 form 1; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P450 PB-1; cytochrome P450, family 2, subfamily C, polypeptide 18; cytochrome P450, family 2, subfamily C, polypeptide 19; cytochrome P450, family 2, subfamily C, polypeptide 8; cytochrome P450, family 2, subfamily C, polypeptide 9; cytochrome P450, family 2, subfamily E, polypeptide 1; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19; cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8; cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1; Cytochrome P450-11A; Cytochrome P450-254C; Cytochrome P450-6b/29c; Cytochrome P450-J; cytochrome P450A; cytochrome P450j; Fenbendazole monooxygenase (4'-hydroxylating); flavoprotein-linked monooxygenase; IIC2; mephenytoin 4'-hydroxylase; Mephenytoin 4-hydroxylase; microsomal monooxygenase; microsomal monooxygenase; xenobiotic monooxygenase; P450 form 1; S-mephenytoin 4-hydroxylase; unnamed protein product; unspecific monooxygenase; xenobiotic monooxygenase
Gene Aliases: CPC8; CPC9; CPCI; CPCJ; CPE1; CYP2C; CYP2C10; CYP2C17; CYP2C18; CYP2C19; CYP2C8; CYP2C8DM; CYP2C9; CYP2E; CYP2E1; CYPIIC17; CYPIIC19; CYPIIC8; CYPIIC9; MP-12/MP-20; P450-2C9; P450-6B/29C; P450-J; P450C2C; P450C2E; P450IIC17; P450IIC19; P450IIC9
UniProt ID: (Human) P33260, (Human) P33261, (Human) P10632, (Human) P11712, (Human) P05181
Entrez Gene ID: (Human) 1562, (Human) 1557, (Human) 1558, (Human) 1559, (Human) 1571
monooxygenase activity
iron ion binding
arachidonic acid epoxygenase activity
retinoic acid 4-hydroxylase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
oxygen binding
heme binding
metal ion binding
linoleic acid epoxygenase activity
steroid hydroxylase activity
(S)-limonene 6-monooxygenase activity
(S)-limonene 7-monooxygenase activity
enzyme binding
(R)-limonene 6-monooxygenase activity
long-chain fatty acid omega-1 hydroxylase activity
protein binding
caffeine oxidase activity
estrogen 16-alpha-hydroxylase activity
arachidonic acid 14,15-epoxygenase activity
arachidonic acid 11,12-epoxygenase activity
estrogen 2-hydroxylase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
4-nitrophenol 2-monooxygenase activity
Hsp70 protein binding
Hsp90 protein binding
long-chain fatty acid metabolic process
lipid metabolic process
fatty acid metabolic process
terpenoid metabolic process
xenobiotic metabolic process
steroid metabolic process
monoterpenoid metabolic process
epoxygenase P450 pathway
monocarboxylic acid metabolic process
xenobiotic catabolic process
omega-hydroxylase P450 pathway
cholesterol metabolic process
estrogen metabolic process
arachidonic acid metabolic process
urea metabolic process
long-chain fatty acid biosynthetic process
icosanoid biosynthetic process
oxidative demethylation
cellular organofluorine metabolic process
lipid hydroxylation
response to bacterium
carbon tetrachloride metabolic process
benzene metabolic process
4-nitrophenol metabolic process
halogenated hydrocarbon metabolic process
retinol metabolic process
retinoic acid metabolic process
linoleic acid metabolic process
organic acid metabolic process
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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