|Immunocytochemistry (ICC)||5 µg/ml|
|Immunofluorescence (IF)||5 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:500|
|Immunohistochemistry (IHC)||See 7 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Human Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide corresponding to residues on the C-term of human CK5|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-14473 targets Cytokeratin 5 in IHC (P) applications and shows reactivity with Human samples.
The MA5-14473 immunogen is a synthetic peptide corresponding to residues on the C-term of human CK5.
Twenty human cytokeratins are divided into acidic (pI<5.7) and basic (pI>6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of cytokeratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of cytokeratins as markers in cancer research and tumor identification. Point mutations in cytokeratin-5 gene may cause Epidermolysis Bullosa Simplex and Dowling-Degos disease. cytokeratin-5 is expressed in most epithelioid and biphasic mesotheliomas, thymoma, squamous and other carcinomas. It is related to cytokeratin-6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 58 kDa cytokeratin; CK-5; cytokeratin 5; Cytokeratin-5; Dowling-Meara/Kobner/Weber-Cockayne types); epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin; keratin 5 (epidermolysis bullosa simplex; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin complex 2, basic, gene 5; Keratin, type II cytoskeletal 5; Keratin-5; krt5; tuftelin interacting protein 8; type II cytoskeletal 5; Type-II keratin Kb5
Gene Aliases: 3300001P10Rik; AW146334; CK5; DDD; DDD1; EBS2; K5; Krt2-5; KRT5; KRT5A; Tfip8
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