|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
|Immunohistochemistry (IHC)||See 11 publications below|
|Miscellaneous PubMed (MISC)||See 5 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 3 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Cytokeratin 5 (Human).|
|Storage buffer||PBS with BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-91106 detects Cytokeratin 5 + 6 from human samples.
MA1-91106 has been successfully used in immunohistochemistry (paraffin tissue) applications. Product requires high temperature antien unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
The MA1-91106 immunogen is Cytokeratin 5 (Human).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 58 kDa cytokeratin; CK-5; CK-6A; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; K6A; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6A, , type II; keratin 6A, type II; keratin K6h; Keratin type II cytoskeletal 5; Keratin type II cytoskeletal 6A; Keratin type II cytoskeletal 6B; keratin, epidermal type II, K6A; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; Keratin-5; Keratin-6A; keratin-6C; KRT5; KRT6A; KRT6B; KRT6D; KRTL1; type-II keratin Kb12; Type-II keratin Kb5; Type-II keratin Kb6
Gene Aliases: CK-6C; CK-6E; CK5; CK6A; CK6C; CK6D; DDD; DDD1; EBS2; K5; K6A; K6C; K6D; KRT5; KRT5A; KRT6A; KRT6C; KRT6D; PC3
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