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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:10,000-1:50,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:200-1:800 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | - |
Flow Cytometry (Flow) |
0.2 µg/1x10^6 cells | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Cytokeratin 6A Fusion Protein Ag0882 (364-564 aa encoded by BC008807) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.21 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: QVTAGRHGD DLRNTKQEIA EINRMIQRLR SEIDHVKKQC ANLQAAIADA EQRGEMALKD AKNKLEGLED ALQKAKQDLA RLLKEYQELM NVKLALDVEI ATYRKLLEGE ECRLNGEGVG QVNISVVQST VSSGYGGASG VGSGLGLGGG SSYSYGSGLG VGGGFSSSSG RAIGGGLSSV GGGSSTIKYT TTSSSSRKSY KH (364-564 aa encoded by BC008807)
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 60-kDa keratin; CK-6A; CK-6D; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Hom s 5; K6A; K6a keratin; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 6A, , type II; keratin 6A, type II; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, gene 6a; keratin K6; keratin K6h; keratin, epidermal type II, K6A; Keratin, type II cytoskeletal 6A; Keratin-6-alpha; Keratin-6A; keratin-6C; mK6-alpha; type-II keratin Kb12; Type-II keratin Kb6
Gene Aliases: 2310016L08Rik; CK-6A; CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; Ker2; Krt2-6; Krt2-6a; Krt2-6c; Krt6; KRT6A; KRT6C; KRT6D; mK6[a]; MK6a; PC3
UniProt ID: (Human) P02538, (Mouse) P50446, (Rat) Q4FZU2
Entrez Gene ID: (Human) 3853, (Mouse) 16687, (Rat) 683313
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