|Immunohistochemistry (Frozen) (IHC (F))||1:100-1:1000|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 44 and 319 of Human Cytokeratin 7|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29033 targets Cytokeratin 7 in IF, IHC (F), IHC (F), IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-29033 immunogen is recombinant fragment corresponding to a region within amino acids 44 and 319 of Human Cytokeratin 7.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 55K type II cytoskeletal; CK-7; CK7; cytokeratin 7; Cytokeratin-7; K2C7; K7; keratin; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Sarcolectin; SCL; simple epithelial type I; type II cytoskeletal 7; type II mesothelial keratin K7; Type-II keratin Kb7
Gene Aliases: CK7; K2C7; K7; KRT7; SCL
UniProt ID: (Human) P08729
Entrez Gene ID: (Human) 3855
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