MA5-11986 targets Cytokeratin 7 in IHC (P) applications and shows reactivity with Human samples.
The MA5-11986 immunogen is oTN II ovarian carcinoma cell line.
Cytokeratin 7 is a basic cytokeratin which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. Antibody to cytokeratin is useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
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Protein Aliases: 55K type II cytoskeletal; CK-7; cytokeratin 7; Cytokeratin-7; K7; keratin; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Sarcolectin; simple epithelial type I; type II cytoskeletal 7; type II mesothelial keratin K7; Type-II keratin Kb7
Gene Aliases: CK7; K2C7; K7; KRT7; SCL
UniProt ID: (Human) P08729
Entrez Gene ID: (Human) 3855