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Product Details
18-0234
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
Class
Monoclonal
Type
Antibody
Clone
OV-TL12/30
Immunogen
OTN11 human ovarian carcinoma cells.
Conjugate
Form
Liquid
Concentration
0.03755 mg/mL
Purification
purified
Storage buffer
PBS with 1% BSA
Contains
0.1% sodium azide
Storage conditions
2-8°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2925244
Product Specific Information
The 54 kDa protein, cytokeratin 7, is found in most glandular and transitional epithelia. It has detected cytokeratin 7 in a large number of epithelial cell types, including many ductal and glandular epithelia by immunohistochemistry of paraffin-embedded tissue. Primarily, cytokeratin 7 antibody does not react with stratified squamous epithelia but is reactive with transitional epithelium of the urinary tract. Positive tissue: Pancreas/bladder cancer. This antibody is specific for cytokeratin 7, and does not exhibit cross-reactivity with other filament types, including vimentin, desmin, glial fibrillary acidic protein and neurofilament protein.
Expected Staining Pattern: Cytoplasmic
Target Information
Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CK-7; cytokeratin 7; Cytokeratin-7; K7; keratin 7, type II; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 7; Keratin-7; Sarcolectin; type II mesothelial keratin K7; Type-II keratin Kb7
Gene Aliases: CK7; K2C7; K7; KRT7; SCL
UniProt ID: (Human) P08729
Entrez Gene ID: (Human) 3855
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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