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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgM|
|Immunogen||Cytoskeletal extract of human hepatocellular carcinoma cell line Hep3B.|
|Storage buffer||tissue culture supernatant|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:10-25|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-25|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA1-26238 detects Cytokeratin 8 from human samples.
MA1-26238 has been successfully used in immunohistochemistry (paraffin and frozen) procedures.
The MA1-26238 immunogen is cytoskeletal extract of human hepatocellular carcinoma cell line Hep3B.
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Malignant transformation of adenomyoepithelioma of the breast by a monophasic population: a report of two cases and review of literature.
MA1-26238 was used in immunohistochemistry to report on two cases of malignant transformation of adenomyoepithelioma of the breast by a monophasic population
|Marian C,Boila A,Soanca D,Malau M,Podeanu DM,Resetkova E,Stolnicu S||APMIS : acta pathologica, microbiologica, et immunologica Scandinavica (121:272)||2013|
CARD2; CK8; CYK8; cytokeratin-8; K2C8; keratin 8, type II; KO; type-II keratin Kb8
CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT8