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Product Details
PA5-67702
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human Cytokeratin 81/86.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2691466
Target Information
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ghHb1; ghHKb1; Hair keratin K2.11; Hair keratin K2.9; hard keratin, type II, 1; hard keratin, type II, 6; K81; K86; keratin 81, type II; keratin 86, type II; keratin protein HB6; Keratin, hair, basic, 1; keratin, hair, basic, 6 (monilethrix); Keratin, type II cuticular Hb1; Keratin, type II cuticular Hb6; Keratin-81; Keratin-86; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type II hair keratin Hb6; Type-II keratin Kb21; Type-II keratin Kb26
Gene Aliases: ghHkb1; Hb-1; HB1; HB6; hHAKB2-1; K86; KRT81; KRT86; KRTHB1; KRTHB6; MLN137; MNX
UniProt ID: (Human) Q14533, (Human) O43790
Entrez Gene ID: (Human) 3887, (Human) 3892
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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