|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse|
|Immunogen||Human hair keratins from P3X63Ag. 8.653 cells|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunohistochemistry (PFA fixed) (IHC (PFA))||Assay Dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 5 publications below|
MA1-5765 detects Cytokeratin, AE13 in human and mouse samples.
MA1-5765 has been successfully used in Western blot, immunocytochemistry, immunofluorescence and immunohistochemistry procedures.
The MA1-5765 immunogen is human hair keratins.
This antibody reacts with acidic 44-46 kDa hair cortex keratins.
Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Metastatic desmoplastic malignant melanoma associated with low-grade myofibroblastic sarcoma.
MA1-5765 was used in immunohistochemistry to report on a case of metastatic desmoplastic malignant melanoma associated with low-grade myofibroblastic sarcoma
|Kacerovska D,Michal M,Kutzner H,Rychnovsky J,Kazakov DV||The American Journal of dermatopathology (31:490)||2009|
Crystal-deficient alveolar soft-part sarcoma with cutaneous involvement: a case report.
MA1-5765 was used in immunohistochemistry to report on a case of crystal-deficient alveolar soft-part sarcoma with cutaneous involvement
|Kacerovska D,Michal M,Nemcova J,Vanecek T,Kreuzberg B,Mrazkova P,Koudela K,Kazakov DV||The American Journal of dermatopathology (31:272)||2009|
Detection of micrometastases and skip metastases with ex vivo sentinel node mapping in carcinoma of the colon and rectum.
MA1-5765 was used in immunohistochemistry to study micrometastases and skip metastases in carcinoma of the colon and rectum
|Yagci G,Unlu A,Kurt B,Can MF,Kaymakcioglu N,Cetiner S,Tufan T,Sen D||International journal of colorectal disease (22:167)||2007|
Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor (HUMARA) locus as a marker.
MA1-5765 was used in immunohistochemistry to investigate clonality of sclerosing polycystic adenosis by human androgen receptor polymorphism
|Skálová A,Gnepp DR,Simpson RH,Lewis JE,Janssen D,Sima R,Vanecek T,Di Palma S,Michal M||The American journal of surgical pathology (30:939)||2006|
Cutaneous lymphoid hyperplasia and other lymphoid infiltrates of the breast nipple: a retrospective clinicopathologic study of fifty-six patients.
MA1-5765 was used in immunohistochemistry to study the clinicopathological spectrum of lymphoproliferations and other lymphoid infiltration of the breast nipple
|Boudova L,Kazakov DV,Sima R,Vanecek T,Torlakovic E,Lamovec J,Kutzner H,Szepe P,Plank L,Bouda J,Hes O,Mukensnabl P,Michal M||The American Journal of dermatopathology (27:375)||2005|