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Product Details
H00001635-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG3, kappa
Class
Monoclonal
Type
Antibody
Clone
4B9
Immunogen
DCTD (NP_001912.2, 69 a.a. approximately 178 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Sequence of this protein is as follows: RTAENKLDTK YPYVCHAELN AIMNKNSTDV KGCSMYVALF PCNECAKLII QAGIKEVIFM SDKYHDSDEA TAARLLFNMA GVTFRKFIPK CSKIVIDFDS INSRPSQKLQ
Target Information
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dCMP deaminase; Deoxycytidylate deaminase
Gene Aliases: DCTD
UniProt ID: (Human) P32321
Entrez Gene ID: (Human) 1635
Molecular Function:
deaminase
hydrolase
metabolite interconversion enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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