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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant full length human DCTN1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 150 kDa.
Purity is >95% by SDS-PAGE.
Dynactin, a multisubunit complex, is a cytoplasmic dynein-interacting protein that functions as the 'receptor' for the dynein microtubule motor. Dynactin-dynein binding may be required for most, if not all, cytoplasmic dynein driven activities and is thought to contribute to dynein's functional diversity. Dynactin, enriched in neurons, also binds to microtubules and has been shown to function in diverse processes, including organelle transport, formation of the mitotic spindle and cytokinesis. Dynactin subunits include p22, p50, p62, p150, (also designated Glued), and Arp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
150 a dynein associated polypeptide; 150 a dynein-associated polypeptide; 150 kDa dynein-associated polypeptide; DAP 150; DAP-150; DAP150; DCTN 1; DCTN1; DP 150; DP-150; DP150; Dynactin 1; Dynactin 1 (p150 Glued (Drosophila) homolog); dynactin 1 (p150 glued homolog Drosophila); dynactin 1 (p150, glued homolog, Drosophila); dynactin 1, retrograde axonal transport; Dynactin subunit 1; Dynactin1; HMN7B; p135; p150 glued; p150 Glued (Drosophila) homolog; p150 glued homolog; p150(GLUED) DROSOPHILA HOMOLOG OF; p150-glued; p150glued
AL022633; DAP-150; DCTN1; DP-150; Glued; P135; p150; p150<glued>