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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human DCTN4 (amino acids: 57-298) expressed in E. Coli.|
|Storage buffer||PBS with 0.05% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:200 - 1:400|
|Immunocytochemistry (ICC)||1:200 - 1:1000|
|Immunofluorescence (IF)||1:200 - 1:1000|
|Immunohistochemistry (IHC)||1:200 - 1:1000|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17065 targets DCTN4 in FACS, ICC, IHC, IF and WB applications and shows reactivity with Human samples.
The MA5-17065 immunogen is purified recombinant fragment of human DCTN4 (amino acids: 57-298) expressed in E. Coli.
MA5-17065 detects DCTN4 which has a predicted molecular weight of approximately 52.3kDa.
Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dynactin 4 (p62); dynactin p62 subunit; dynactin subunit p62
DCTN4; DYN4; P62