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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG|
|Immunogen||Synthetic peptide conugated to protein carrier.|
|Storage buffer||PBS, pH 7.2|
|Storage Conditions||-80° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-23335 detects DDB1 in Human samples.
MA1-23335 has been successfully used in ELISA and Western blot procedures.
The MA1-23335 immunogen is a synthetic peptide conugated to protein carrier. The mice were immunized with a combination of N & C peptide. The Swiss Prot ID is Q16531. The exact region recognized by this product has not yet been determined.
The DNA damage-binding protein from HeLa cells is associated with polypeptides of relative mass 124,000 (DDB1) and 41,000 (DDB2) as determined by SDS-polyacrylamide gels. To test whether the DNA-repair defect in the subset of XPE patients that lack DNA damage-binding activity is caused by a defect in DDB, Keeney et al. (1994) injected purified human DDB protein into XPE cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
damage-specific DNA binding protein 1, 127kDa; DDB p127 subunit; DDBA; DNA damage-binding protein a; HBV X-associated protein 1; UV-damaged DNA-binding factor; UV-damaged DNA-binding protein 1; UV-DDB 1; UV-DDB1; XAP-1; XAP1; xeroderma pigmentosum group E-complementing protein; XPCE; XPE; XPE-BF; XPE-binding factor
DDB1; DDBA; UV-DDB1; XAP1; XPCE; XPE; XPE-BF