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Immunogen sequence: GSENVDDNNQ LFRFPATSPL KTLPRRYPEL RKNNIENFSK DKDSIFKLRN LSRRTPKRHG LHLSQENGEK IKHEIINEDQ ENAIDNRELS QEDV
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cell cycle control protein SDP35; DEP domain-containing protein 1A
Gene Aliases: DEP.8; DEPDC1; DEPDC1-V2; DEPDC1A; SDP35
UniProt ID: (Human) Q5TB30
Entrez Gene ID: (Human) 55635
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